Helping The others Realize The Advantages Of ceesdekker.net
Helping The others Realize The Advantages Of ceesdekker.net
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Halfway as a result of his occupation, Cees Dekker reinvented himself. After several years of hardcore physics, he shifted his concentrate to ‘nanobiology’ for the flip with the millennium. A term he coined himself, for a make a difference of actuality.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I
Non-equilibrium folding of personal DNA molecules recaptured around 1000 occasions in the reliable condition nanopore
De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt about het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft fulfilled veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de
SMC complexes can pass Actual physical roadblocks larger than their ring measurement, indicating a nontopological mechanism for DNA loop extrusion
Numerous associated developments followed, exactly where our group set up various transistor variants including solitary-electron transistors at area temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled a number of transistors into smaller evidence-of-theory electronic circuits.
Finding out DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.
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Dekker begun his investigation on single carbon nanotubes in 1993 when he arrange a whole new line of analysis to study electrical transportation via one natural molecules between nanoelectrodes. In 1996 a breakthrough was recognized with carbon nanotubes. This was accomplished inside of a collaboration Together with the team of Nobel laureate Richard Smalley. STM and nanolithography tactics were accustomed to demonstrate that these nanotubes are quantum wires at The only-molecule level, with fantastic physical Houses.
Given that 2000 he moved to one-molecule biophysics and nanobiology, with investigation from research of DNA loop extrusion and supercoiling to DNA translocation by nanopores. A lot more recently his exploration has focused on finding out chromatin structure and mobile division with bacteria on chip, when he can also be aiming to in the end Make synthetic cells from the bottom up.
Cees Dekker is Distinguished University Professor at TU Delft. Properly trained to be a physicist, he pioneered nanotechnology with lots of discoveries on carbon nanotubes within the nineties. Given that 2000, he moved to single-molecule biophysics and nanobiology. His present analysis focuses on (i) nanopores for protein sequencing; (ii) chromosome construction, in particular SMC motor protein; and (iii) building a dwelling artificial cell from lifeless molecules. Dekker is an elected member of your KNAW and fellow to your APS plus the IOP.
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Illustration (2) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in grey, the rim with the pore is highlighted in crimson, and also a 3D rendering from the movement of the DNA rod is shown.